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Tobacco packaging should not function as mini-billboards promoting tobacco use. On the flip side, the industry association representing convenience stores said plain packaging increases the appeal of contraband tobacco products and makes them harder to distinguish from legally marketed ones

These differences in dimensions enable the manufacturer to segment the market, distinguish their product, and cater to various consumers preferences in terms of the length of smoking and appearance

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Data analysis Unsupervised principal component analysis (PCA) was first used to observe the overall distribution of samples and the stability of the analysis, followed by supervised partial least-squares discriminant analysis (PLS-DA) and orthogonal partial least-squares discriminant analysis (OPLS-DA) used to distinguish the differences in metabolic profiles